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pentobarbital will lower the level or influence of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Strong or reasonable CYP3A4 inducers could enhance rate of diazepam elimination; as a result, efficacy of diazepam can be lowered.pentobarbital will reduce the level or result of alosetron by affecting hepa